Asthma Cost Model¶

Data¶

Cost Due to Asthma Exacerbations¶

The data used in the cost model comes from the study [Yaghoubi, 2020], in Table I:

Variable	Value
Direct costs of exacerbation by severity: mild	$130 USD
Direct costs of exacerbation by severity: moderate	$594 USD
Direct costs of exacerbation by severity: (very) severe	$9900 USD

Note

In the paper, severe exacerbations are equivalent to our definition of very severe exacerbations. Thus, we are missing the cost of severe exacerbations. To account for this, we defined the cost of a severe exacerbation as:

\[\begin{split}\text{cost}_E(\text{severe}) &= \exp\left(\dfrac{ \text{log}(\text{cost}_E(\text{moderate})) + \text{log}(\text{cost}_E(\text{very severe})) }{2}\right) \\ &= \$2425 \text{ USD}\end{split}\]

Cost Due to Asthma Control Levels¶

The data used for the cost by asthma control level also comes from the study [Yaghoubi, 2020], in Table I:

Variable	Value
Annual direct costs of well-controlled asthma	$2372 USD
Annual direct costs of not-well-controlled asthma	$2965 USD
Annual direct costs of uncontrolled asthma	$3127 USD

Model¶

\[\text{cost} = \sum_{S=1}^4 n_E(S) \cdot \text{cost}_E(S) + \sum_{L=1}^3 P(L) \cdot \text{cost}_C(L)\]

where:

$n_E(S)$ is the number of exacerbations at severity level $S$
$\text{cost}_E(S)$ is the cost of an exacerbation at severity level $S$
$P(L)$ is the probability of being at asthma control level $L$
$\text{cost}_C(L)$ is the cost of being at asthma control level $L$